The District of Columbia, commonly referred to as D.C., is the capital of the United States and is located on the Potomac River between Maryland and Virginia. The city is home to all three branches of the federal government and is the center of the nation's political life. The answer to the crossword puzzle is CALI, which is the capital of Colombia, located in the southwestern part of the country. It is the third-largest city in Colombia and is known for its vibrant culture, colonial architecture, and beautiful landscapes.