The term 'DESTROY TOTALLY' can be expressed in three different ways: EXTIRPATE (9 letters), RUIN (4 letters), and EXTERMINATE (11 letters). EXTIRPATE means to remove or destroy completely, often referring to the removal of a plant or animal species from a particular area. RUIN is defined as the destruction or disintegration of something, usually caused by natural forces or human activity. EXTERMINATE is a more extreme form of destruction, meaning to completely destroy or annihilate something, often referring to the mass killing of a population.