The crossword solution for the term D.O.E. PART: ABBR. is ENER, which stands for Energy. The U.S. Department of Energy (DOE) is a federal agency that was established in 1977 to promote energy security and address the environmental impacts of energy production and use. It is responsible for researching and developing clean energy technologies, managing the nation's nuclear weapons program, and providing energy assistance to low-income households.