The crossword solution for the term COMPLICATION, TO HAMLET is RUB. This is a reference to the famous Shakespearean play Hamlet, in which the protagonist is faced with a number of difficult decisions and moral dilemmas. The term 'RUB' is used to describe the obstacles and difficulties that Hamlet must overcome in order to reach his ultimate goal. In this context, the term 'complication, to Hamlet' can be interpreted as the various challenges and obstacles that Hamlet must face in order to achieve his desired outcome.