The term 'City Slicker' is a colloquialism used to describe someone who is from a city and is unfamiliar with rural life. The crossword solutions for this term are 'DUDE' (4 letters) and 'Drugstore Cowboy' (15 letters). 'DUDE' is a slang term used to refer to a man, usually one who is fashionable or stylish. 'Drugstore Cowboy' is a 1989 film starring Matt Dillon as a drug addict living in Seattle during the 1970s. The film follows his journey as he struggles to survive and find redemption.