The term CITY HOLY is composed of three crossword solutions: QOM (3 letters), MECCA (5 letters), and MEDINA (6 letters). Qom is a city in Iran, which is considered to be one of the holiest cities in Shia Islam. Mecca is a city in Saudi Arabia, which is the holiest city in Islam and the birthplace of the Prophet Muhammad. Medina is also a city in Saudi Arabia, which is the second holiest city in Islam and the burial place of the Prophet Muhammad.