The term 'CHANGED THE COURSE OF' can be summarized by the crossword solution 'RESHAPED, ' which means to alter or modify something. This could refer to a variety of things, such as a plan, an opinion, or even a physical object. It implies that the original form of the thing has been altered in some way, and the new form is different from the original. In this context, it could mean that something has been altered in order to change the course of events or the outcome of a situation.