Change, chemically can be defined as a chemical reaction, which is a process in which one or more substances are converted into one or more different substances. The crossword solutions for this term are REACT (5 letters), REACTS (6 letters), and INERT (5 letters). REACT refers to the act of undergoing a chemical reaction, while REACTS is the present tense of the verb 'to REACT'. INERT, on the other hand, means not reacting or not capable of reacting, which is the opposite of the other two solutions.