CARLE is an acronym for the Children's Asthma Research and Education (CARE) program, which was founded in 1998 by Dr. Eric Carle, a renowned children's author and illustrator. The CARE program works to improve the quality of life for children with asthma and their families through research, education, and advocacy. The program also provides resources to help families manage asthma and reduce the risk of asthma-related emergencies.