Canasta Plays is a card game that involves melding cards together to form sets. The term 'MELDS' refers to the process of combining three or more cards of the same rank, such as three kings or four aces. Players can also create sequences of cards in the same suit, such as a run of five consecutive hearts. The goal of the game is to create MELDS and score points by playing them on the table. The player with the most points at the end of the game wins.