Breakthroughs are significant advances or accomplishments that have a major impact on a particular field. The term 'breakthroughs' can refer to a variety of different things, such as scientific discoveries, technological innovations, or social movements. The crossword solution for the term 'breakthroughs' is 'firsts, ' which refers to the first time something has been achieved. This could be the first time a certain technology has been developed, the first time a certain scientific discovery has been made, or the first time a certain social movement has been successful.