The crossword solution for the term ASIMOV TOPIC, OFTEN is 'ROBOT'. Isaac Asimov was a renowned science fiction writer who wrote extensively about robots and their implications for humanity. He is best known for his Three Laws of Robotics, which are a set of rules designed to ensure that robots do not harm humans. Asimov's works often explore the idea of robots as companions or even replacements for humans, and the ethical implications of such a relationship.