The Arquette family is a well-known Hollywood family. Rosanna Arquette is an actress, director, and producer who has starred in films such as Desperately Seeking Susan and Pulp Fiction. Her brother, David Arquette, is an actor, director, and professional wrestler who has appeared in films such as Scream and Eight Legged Freaks. Patricia Arquette is an actress and activist who won an Academy Award for her role in Boyhood. Finally, ALEXIS Arquette is an actress, cabaret performer, and transgender activist.