The Appian Way, also known as the Via Appia, was an ancient Roman ROAD that connected Rome to Brindisi in southeastern Italy. It was constructed in 312 BC by the Roman censor Appius Claudius Caecus and was the first major Roman ROAD built. The term 'Appian Way, E.g.' is used to refer to any long and important ROAD or JOURNEY. The crossword solution for this term is ITER, which is a Latin word meaning 'JOURNEY' or 'ROAD'.