The term 'AMOUNT TO TAKE' can be broken down into two crossword solutions: DOSE (4 letters) and DOSAGE (6 letters). DOSE is a noun that refers to the quantity of a medicine, drug, or other substance to be taken at one time. DOSAGE is a noun that refers to the rate at which a medicine, drug, or other substance is taken over a specific period of time. Both terms are used in the medical field to refer to the amount of a substance that should be taken by a patient.