The term ALKA-SELTZER SOUND is composed of four words related to the popular ANTACID medication. FIZZ is a sound made when a substance is dropped into a liquid, which is what happens when Alka-Seltzer is added to water. PLOP is another sound made when a substance is dropped into a liquid. SPEEDY is a reference to the fast-acting relief that Alka-Seltzer provides. ANTACID is the type of medication that Alka-Seltzer is, and BAYER is the company that manufactures it.