The Adriatic and Aegean Seas are two large bodies of water located in the Mediterranean region. The Adriatic SEA is located between Italy and the Balkan Peninsula, while the Aegean SEA is located between Greece and Turkey. Both seas are important for trade and transportation, as well as for their rich marine life. The answer to the crossword puzzle is SEA, a three-letter word that describes both the Adriatic and Aegean Seas.