Isabel Sanford was an American actress best known for her role as Louise 'Weezy' Mills Jefferson on the CBS sitcom The Jeffersons. She won an Emmy Award for Outstanding Lead Actress in a Comedy Series for her performance in 1981. She also appeared in films such as Guess Who's Coming to Dinner and The Heartbreak Kid. Sanford was also a successful stage actress, appearing in productions such as A Raisin in the Sun and The Miracle Worker.