Tuscany is a region in central Italy known for its rolling hills, vineyards, and medieval towns. Three of the cities in Tuscany that are featured in this crossword are Pisa (4 letters), Siena (5 letters), and Lucca (5 letters). Pisa is most famous for its leaning tower, while Siena is known for its Gothic architecture and Palio horse race. Lucca is a walled city with many churches and towers. Etruria (7 letters) is an ancient region in Tuscany, and the ARNO (4 letters) is a river that flows through the region.